Sinopsis

Han pasado ya veinte años desde que Harry y Lloyd se conocieran, pero ninguno de los dos parece haber madurado. Harry tiene una hija a la que apenas conoce y, necesitando un trasplante de riñón, intenta localizarla para pedirle que le done uno de los suyos. Para esta aventura necesitará la ayuda de su inseparable Lloyd. Sin embargo, éste no se encuentra en muy buen estado físico ni psicológico desde que Mary le rechazó. Harry tendrá que prepararle antes de vivir numerosas aventuras durante el viaje.



Bobby Farrelly Bobby Farrelly Director
Peter Farrelly Peter Farrelly Director
Bradley Thomas Bradley Thomas Productor
Bobby Farrelly Bobby Farrelly Productor
Peter Farrelly Peter Farrelly Productor
Joey McFarland Joey McFarland Productor
Riza Aziz Riza Aziz Productor
Bobby Farrelly Bobby Farrelly Guionista
Peter Farrelly Peter Farrelly Guionista
Mike Cerrone Mike Cerrone Guionista
Bennett Yellin Bennett Yellin Guionista
John Morris John Morris Guionista
Sean Anders Sean Anders Guionista
Jim Carrey Jim Carrey Lloyd Christmas
Jeff Daniels Jeff Daniels Harry Dunne
Steve Tom Steve Tom Dr. Pinchelow
Rob Riggle Rob Riggle Travis / Captain Lippincott
Don Lake Don Lake Dr. Meldman
Patricia French Patricia French Ms. Sourpuss
Gregory Fears Gregory Fears Man at Gas Station
Tembi Locke Tembi Locke Dr. Walcott
Paul Blackthorne Paul Blackthorne Emergency Room Doctor
Lindsay Ayliffe Lindsay Ayliffe Professor Garabedian
Matthew Cardarople Matthew Cardarople Inventor No. 1
Bill Murray Bill Murray Ice Pick
Grant James Grant James Mr. Stainer
Taylor St. Clair Taylor St. Clair Mrs. Steiner
Erin Allin O'Reilly Erin Allin O'Reilly Asylum Nurse No. 1
Tim Campione Tim Campione Conference Attendee
Jennifer Cocker Jennifer Cocker Young Inventor
Derrick Dean Derrick Dean Hospital Visitor
Garret H. Dumas Garret H. Dumas Conference Patron
William Goodrum William Goodrum Prom Singer
Walter Hendrix III Walter Hendrix III Street Patron
Lauren Henneberg Lauren Henneberg Upscale Guest
Michael Jaegers Michael Jaegers Computer Convention Attendee
Angela Kerecz Angela Kerecz Waitress
Aaron Kischnick Aaron Kischnick Ken Philanthropist
Rob Koebel Rob Koebel Officer Stone
Taylor McPherson Taylor McPherson Electronic Convention Attendee
David Pascua David Pascua Mariachi Trumpet Player
Josh Turner Josh Turner KEN Convention Employee
Stefan Walker Armstrong Stefan Walker Armstrong Audience Member
Walt Arnett Walt Arnett KEN Audience Member
Paul Bednarz Paul Bednarz KEN Convention Employee
Erika Bierman Erika Bierman Fanny at Age 13
Derek Blankenship Derek Blankenship Store Clerk
Kassidy Claire Kassidy Claire Fanny at Age 5
Jesse Clark Jesse Clark Club-Goer
Carly Craig Carly Craig Young Fraida
Bryan Dilbeck Bryan Dilbeck Dr. Dilbeck
Abigail Gamache Abigail Gamache Prom Attendee
Dalton E. Gray Dalton E. Gray Young Harry
Llauryn P. Hendrix Llauryn P. Hendrix Conference Patron
Ron Hudson Ron Hudson Club Patron
Kathlene Huslin Kathlene Huslin KEN Vendor
Erick Reihs Jackson Erick Reihs Jackson Gas Station Patron
Darien Johnson Darien Johnson KEN Convention Attendee
Debi Kimsey Debi Kimsey Knitting Lady on porch
Anthony R. McClara Anthony R. McClara Security Guard
Michael McCrudden Michael McCrudden Audience Member
Richard Melton Richard Melton Chaperone
Maia Moss-Fife Maia Moss-Fife Receptionist
Ryan Nesset Ryan Nesset Pedestrian
Orbert Rogers Orbert Rogers Park Patron
Sade Shearer Sade Shearer Prom Attendee
Dereck Smith Dereck Smith Convention Center Nerd
Jeff Sumner Jeff Sumner Convention Official
Dave Walpole Dave Walpole KEN Converence Attendee
Dave Walpole Dave Walpole KEN Conference Attendee
Christina Michelle Williams Christina Michelle Williams KEN Convention Employee
Brett Wyman Brett Wyman Inventor No. 2
Bennett Wayne Dean Sr. Bennett Wayne Dean Sr. Hospital Visitor
Doris Dean Doris Dean Hospital Visitor
John Deifer John Deifer Mental patient
Jacklyn Edney Jacklyn Edney KEN Con Scientist
David Emmett David Emmett Hospital Visitor
Cody Mark Hanna Cody Mark Hanna Audience Member
John Merical John Merical Neighbor
Barbara Prince Barbara Prince Street Patron
June Shannon June Shannon Harry's Trailer Park Wife
Julius Sharpe Julius Sharpe KEN Conference Attendee